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dc.contributor.authorShakouri, Arash
dc.contributor.authorShoushizadeh, Mohammad Reza
dc.contributor.authorNematpour, Fatemeh
dc.coverage.spatialIranen_US
dc.coverage.spatialOman Seaen_US
dc.coverage.spatialChabahar Bayen_US
dc.date.accessioned2017-11-02T15:29:44Z
dc.date.available2017-11-02T15:29:44Z
dc.date.issued2017
dc.identifier.doi10.5812/jjnpp.32422.
dc.identifier.urihttp://hdl.handle.net/1834/10374
dc.description.abstractSeas and oceans have been recognized as a rich source of metabolites and bioactive compounds with biodiversity and drug activity. These compounds have accumulated in various organisms. Bioactive compounds can be extracted from various animal groups, such as coral, crabs, moss animals, Echinodermata, case-bearers, fishes, and sponges. Objectives: Antimicrobial extracts of the sea cucumber body wall (Stichopus variegatus), collected from Chabahar Bay, were tested for four bacterial, fungal, and yeast species. Methods: The disk diffusion method was used in this study. The McFarland 0.5 standard was used in the preparation of suspensions of the mentioned microorganisms under a hood. Next, the species were cultured with a swab on a Mueller-Hinton agar for bacteria and on a Sabouraud dextrose agar for fungi. Subsequently, the disks, with appropriate concentrations, were placed on microbiological growth media. Results: The results of the study showed that the best effect belonged to the aqueous methanol extract of the sea cucumber body wall, with an 8 mg/mL concentration on E. coli, with an inhibition zone diameter of 12.26 mm. The lowest inhibition zone diameter belonged to the methanol extract of white strands, with a 2 mg/mL concentration on C. albicans and an inhibition zone diameter of 1.16 mm. The n-hexane and chloroform extracts had no effect. Conclusions: Comparison of these tests indicates that sea cucumbers have an innate immunity system, which can be considered a potential source for discovering antimicrobial peptides.en_US
dc.language.isoenen_US
dc.subject.otherStichopus variegatusen_US
dc.subject.otherC. albicansen_US
dc.subject.otherAspergillus nigeren_US
dc.titleAntimicrobial Activity of Sea Cucumber (Stichopus variegatus) Body Wall Extract in Chabahar Bay, Oman Seaen_US
dc.typeJournal Contributionen_US
dc.bibliographicCitation.issue1en_US
dc.bibliographicCitation.titleJundishapur Journal of Natural Pharmaceutical Productsen_US
dc.bibliographicCitation.volume12en_US
dc.description.statusPublisheden_US
dc.format.pagerangepp. 1-5en_US
dc.subject.asfaSea Cucumberen_US
dc.subject.asfaAntimicrobial Activityen_US
dc.subject.asfaExtractsen_US
dc.subject.asfaBody Wallen_US
dc.type.refereedRefereeden_US
refterms.dateFOA2021-01-30T18:48:40Z


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