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State of antioxidant protection and detoxification systems in the tissues of gobies and carp fish after exposure to fungicides of a new generation

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Author
Levina, I.L.
Kuznetsova, L.Ya.
Shcherbakova, N.I.
Zinchuk, O.A.
Publication Editor
Belousov, V.N.
Date
2017

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Alternative Title
Состояние систем антиоксидантной защиты и детоксикации в тканях бычковых и карповых рыб при воздействии фунгицидов нового поколения
Abstract
The effect of two novel carboxamide fungicides, Ethaboxam and Boscalid, on round goby fry and carp fingerlings has been studied. Boscalid is characterized to be highly toxic when applied to round goby fries, Ethaboxam is of medium toxicity to commercial fish species. In the early stages of intoxication (1st - 4th day) the threshold concentrations of the fungicides acted as stressors and resulted in the stimulation of protective systems of the antioxidant protection and detoxification in the liver and gills of carp and round goby tissues, which hindered the development of fungicide intoxication. Intensification of lipid peroxidation processes led to the inhibition of superoxide dismutase activity alongside with the increased activity of catalase, esterases, glutathione-S-transferase, while glutathione content in fish tissues decreased gradually.
Изучено влияние двух фунгицидов нового поколения карбоксамидов – Этабоксама и Боскалида на мальков бычка-кругляка и сеголетков карпа. Показано, что при остром действии высокой степенью токсичности обладал Боскалид для мальков бычка-кругляка, Этабоксам среднетоксичен для промысловых рыб. На ранних стадиях интоксикации (1–4-е сутки) фунгициды в пороговых концентрациях действовали как стресс-факторы и приводили к стимуляции защитных систем антиоксидантной защиты и детоксикации в печени и жабрах карпа, тканях бычка-кругляка, что препятствовало развитию фунгицидной интоксикации. Интенсификация процессов ПОЛ приводила к ингибированию активности супероксиддисмутазы параллельно с усилением активности каталазы, эстераз, глутатион-S-трансферазы, содержание восстановленного глутатиона в тканях рыб постепенно снижалось.
Journal
AzNIIRKH Proceedings
Volume
1
Page Range
pp.179-185
Resource/Dataset Location
http://azniirkh.ru/novosti/sbornik-trudyi-azniirh-vyishel-iz-pechati/
URI
http://hdl.handle.net/1834/17294
Collections
AzNIIRKH Proceedings 2017

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