The marine plant thalassia testudinum possesses anti-inflammatory and analgesic properties
Name:
The marine plant thalassia[1]. ...
Size:
32.90Kb
Format:
PDF
Description:
Published version
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Date
2006
Metadata
Show full item recordAbstract
The natural marine compounds represent a source of new chemical structures and of pharmacological substances with anti-inflammatory activity that will allow to deep in the knowledge of the inflammatory process and in novel mechanisms of action of therapeutic agents. In this work we carry out the study of a extract of a marine plant present in the Cuban coast, Thalassia testudinum (Tt) with the objective of detecting anti-inflammatory and analgesic effects by carrageenan paw oedema, croton oil mouse ear oedema, phospholipase A2 (PLA2) inhibition, cyclo-oxygenase (COX) inhibition and writhing tests. Three fractions, obtained from this extract, were also evaluated in the assay of croton oilinduced ear oedema, PLA2 inhibition, COX inhibition and writhing test. The extract obtained from the Tt plant demonstrated an inhibitory effect in the carrageenan paw oedema. Also, demonstrated inhibitory effect over PLA2 and COX enzyme. Chloroform and butanolic fractions also inhibited mouse ear oedema assay, and COX enzyme, but only the chloroform fraction inhibited the PLA2 enzyme. The extract, butanolic and aqueous fractions inhibited writhing test. We can conclude that the extract, chloroform and butanol fractions shows antiinflammatory properties and the extract and two of the fractions show analgesic effect.Journal
PharmacologyonlineIssue/Article Nr
3